Projects

Ph.D. Projects, Stevens Institute of Technology

• Measuring brain shape changes in aging and neurodegenerative diseases

Integrating a connectome model of the brain into the 3D geometry of a brain to build a physic-informed model of the biomarker abnormality progression in Alzheimer’s disease.

• Numerical analysis of the morphological features of the brain

Developed computational methods to measure the morphometry of the complex brain shape, based on an MRI-based meshed geometry of a brain. The measures include curvature and cortical thickness.

• Connectome-based diffusion model of Alzheimer’s disease

Created a network-based diffusion model of the progression of Alzheimer’s disease by utilizing the Fisher-Kolmogorov reaction-diffusion equation and the discrete brain network model.

• Registration of longitudinal MR images of the brain

Performed multi-step registration on magnetic resonance images of the brain to identify and quantify the shape changes of the brain due to aging and neurodegeneration.

• Building the brain connectome from diffusion tensor images

Generated a network model of the brain, connectome, from the Diffusion-weighted magnetic resonance images to discretize the geometry of the brain into a series of nodes and connections.

M.Sc. Projects, University of Tehran 

• The Mechanical Functions of Uterus and Cervix on Preterm Birth (Thesis)

Investigated the impact of cervical softening and amniotic sac deformation on preterm labor utilizing a patient-specific 3D model. Identified that altered amniotic sac geometry heightened cervical stress, consequently initiating cervical insufficiency and premature delivery.

• Created a prediction model of bone remodeling around an orthopedic screw

Researched the impact of bone screw engineering designs on stress shielding and loosening using a two-dimensional finite element model. Developed parameters to quantify screw-bone load-sharing patterns, revealing design adjustments that reduce screw loosening probability, with implications beyond orthopedic screws.

• Analyzed biomechanical effects of stent material on a stented coronary artery

Explored the performance of biodegradable magnesium alloy coronary stents compared to permanent stainless-steel counterparts using finite element analysis. Evaluated stent behavior during deployment, stress distribution, vessel response, and likelihood of restenosis.